Advances and problems of peptic ulcer drugs.H2 acceptor blocking agent and proton pump inhibitor.
نویسندگان
چکیده
منابع مشابه
Systematic review and meta-analysis of proton pump inhibitor therapy in peptic ulcer bleeding.
OBJECTIVES To review randomised controlled trials of treatment with a proton pump inhibitor in patients with ulcer bleeding and determine the impact on mortality, rebleeding, and surgical intervention. DESIGN Systematic review and meta-analysis. DATA SOURCES Cochrane Collaboration's trials register, Medline, and Embase, handsearched abstracts, and pharmaceutical companies. REVIEW METHODS ...
متن کاملCost-effectiveness of proton pump inhibitor therapy for acute peptic ulcer-related bleeding.
OBJECTIVE The purpose of this investigation was to perform a cost-effectiveness analysis of adjunctive oral and intravenous proton pump inhibitor (PPI) therapies for patients with acute peptic ulcer-related bleeding of sufficient severity to warrant hospitalization. DESIGN Cost-effectiveness investigation. Four clinical scenarios were considered: scenario 1, diagnostic endoscopy with oral PPI...
متن کاملSystematic review and meta-analysis: is 1-week proton pump inhibitor-based triple therapy sufficient to heal peptic ulcer?
AIMS To systematically review the efficacy on ulcer healing of 1-week combination of a proton pump inhibitor plus two antibiotics and to perform a meta-analysis of randomized clinical trials to evaluate whether 7 days of proton pump inhibitor-based triple therapy is sufficient to heal peptic ulcer. METHODS Studies where 1-week proton pump inhibitor-based triple therapy was administered to hea...
متن کاملOral or intravenous proton pump inhibitor in patients with peptic ulcer bleeding after successful endoscopic epinephrine injection.
AIMS We aimed to assess the clinical effectiveness of oral vs. intravenous (i.v.) regular-dose proton pump inhibitor (PPI) after endoscopic injection of epinephrine in patients with peptic ulcer bleeding. METHODS Peptic ulcer patients with active bleeding, nonbleeding visible vessels, or adherent clots were enrolled after successful endoscopic haemostasis achieved by epinephrine injection. Th...
متن کاملRecent advances in peptic ulcer bleeding
Peptic ulcer bleeding remains a common cause of hospital admission, morbidity and mortality. Data published since 2006 illustrate that assessment, endoscopic and pharmacological management, and follow-up strategies can be refined to improve the overall prognosis of peptic ulcer bleeding.
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1994
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.25.327